Yazar "Karahan, Siyami" için listeleme
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Albino farelerde iyonlaştırıcı radyasyonun hepatosit morfolojisi ve prolifere hücre çekirdek antijeni (PCNA) ekspresyonu üzerindeki etkileri
Bu çalısmada, iyonlastırıcı radyasyonun albino farelerde hepatosit proliferasyon oranına etkisinin arastırılması amaçlandı. Normal ve iyonlastırıcı radyasyona maruz kalan albino fare hepatositlerindeki prolifere hücre ... -
Aljinat ile mikroenkapsülasyonu yapılan primer kondrositlerin hidrojel içi ve dışı kondrojenik potansiyelleri
Güçlü, Rumeysa (Kırıkkale Üniversitesi, 2014)Kıkırdak dokusunun tamir yeteneği oldukça sınırlıdır. Bu nedenle, osteoartritis gibi dejeneratif eklem hastalıklarında, hasarlı bölgelere taşıyıcı matriksler içinde kondrosit implantasyonu yapılması en güncel yaklaşımlar ... -
Aromatase expression in the cerebellum of the dog infected with canine distemper virus
Yarim, Murat; Gulbahar, Mustafa Yavuz; Guvenc, Tolga; Karahan, Siyami; Harada, Nobuhiro; Kabak, Yonca Betil; Karayigit, Mehmet Onder (Schluetersche Verlagsgesellschaft Mbh & Co Kg, 2010)Aromatase is the enzyme that catalyzes the biosynthesis of estrogens. It is implicated in neuroprotection. The present study investigated aromatase expression in the cerebellum of dogs infected with canine distemper virus ... -
Autologous stem cell-derived chondrocyte implantation with bio-targeted microspheres for the treatment of osteochondral defects
Bozkurt, Murat; Asik, Mehmet Dogan; Gursoy, Safa; Turk, Mustafa; Karahan, Siyami; Gumuskaya, Berrak; Dogan, Metin (Bmc, 2019)Background Chondral injury is a common problem around the world. Currently, there are several treatment strategies for these types of injuries. The possible complications and problems associated with conventional techniques ... -
Cerebellum progesterone concentration decreased in canine distemper virus infection
Yarim, Gul Fatma; Karahan, Siyami; Yarim, Murat (Elsevier Sci Ltd, 2007)Progesterone has neuroprotective effects including augmentation of myelination in the central and peripheral nervous system. This study was designed to determine if demyelinating lesions in the cerebellum resulting from ... -
Characterization and Evaluation of Triamcinolone, Raloxifene, and Their Dual-Loaded Microspheres as Prospective Local Treatment System in Rheumatic Rat Joints
Ocal, Yigit; Kurum, Baris; Karahan, Siyami; Tezcaner, Aysen; Ozen, Seza; Keskin, Dilek (Elsevier Science Inc, 2014)In this study, injectable microspheres were developed for the local treatment of joint degeneration in rheumatoid arthritis (RA). Microspheres loaded with triamcinolone (TA), a corticosteroid drug, and/or raloxifene (Ral), ... -
Characterization of chondrocytes cultured on catechin-loaded alginate-chitosan scaffolds
Turk, Mustafa; Karahan, Siyami; Cinar, Miyase; Kucuk, Sebnem; Dincel, Gungor Cagdas (Informa Healthcare, 2013)Bovine chondrocytes were seeded into scaffolds of a high molecular weight chitosan and alginate with a pore size of 50-350 mu m with or without catechin. In polymerase chain reaction (PCR), unlike type II, collagen type I ... -
Determination of antioxidants in bovine oviduct epithelial cell culture isolated at different periods of the estrous cycle
Kurum, Aytul; Karahan, Siyami; Kocamis, Hakan; Cinar, Miyase; Ergun, Emel (Scientific Technical Research Council Turkey-Tubitak, 2019)Oxidative stress interferes with oviduct functions including oocyte maturation, capacitation, fertilization, and embryo and gamete transport. This study aimed to determine activity of the antioxidants glutathione peroxidase ... -
Effects Of Ankaferd Blood Stopper-Reinforced Platelet-Rich Fibrin Membrane On Guided Tissue Regeneration In Experimental Bone Defects
Özer, Taha; Aktaş, Alper; Karahan, Siyami (2019)Background and Aim: To evaluate the effects of AnkaferdBlood Stopper added platelet-rich fibrin administered incranial bone defects created in rabbits via histomorphometricassessment.Materials and Method: Four circular 5 ... -
Effects of Local Low-Dose Alendronate Injections Into the Distraction Gap on New Bone Formation and Distraction Rate on Distraction Osteogenesis
Alp, Yunus Emre; Taskaldiran, Alper; Onder, Mustafa Ercument; Karahan, Siyami; Kocyigit, Ismail Doruk; Atil, Fethi; Tekin, Umut (Lippincott Williams & Wilkins, 2017)Bisphosphonates that constrain bone resorption have a direct effect on osteoclast function. In this experimental study, the effects of low-dose local alendronate injections on the distraction gap (DG) in rabbit mandible ... -
Effects of water quality and fish size on toxicity of methiocarb, a carbamate pesticide, to rainbow trout
Altinok, Ilhan; Capkin, Erol; Karahan, Siyami; Boran, Muhammet (Elsevier, 2006)The acute toxicity of methiocarb in juvenile rainbow trout (Oncorhynchus mykiss, 3.25 +/- 0.79 g) was evaluated in glass aquaria under static conditions. Nominal concentrations of methiocarb in the toxicity test ranged ... -
Evaluation of melamine and cyanuric acid cytotoxicity: an in vitro study on L929 fibroblasts and CHO cell line
Melekoglu, Abdullah; Ekici, Husamettin; Arat, Esra; Karahan, Siyami (ANKARA UNIV PRESS, 2020)Melamine and its metabolites pose health concern as they are used in various industrial products including feed and drugs. There are a limited number of studies on melamine and cyanuric acid cytotoxicity and cellular damage ... -
Fabrication and characterization of gold-nanoparticles/chitosan film: a scaffold for L929-fibroblasts
Turk, Mustafa; Tamer, Ugur; Alver, Erol; Ciftci, Hakan; Metin, Aysegul U.; Karahan, Siyami (Taylor & Francis Ltd, 2013)The objective of the present study was to fabricate a gold nanoparticle crosslinked chitosan (Ch/AuNPs) composite film simple and to evaluate its use as a carrier matrix for L929-fibroblasts. L929-fibroblasts were seeded ... -
Histomorphometric examination of the pineal gland in foals and adult horses
Bolat, Durmus; Kurum, Aytul; Bahar, Sadullah; Karahan, Siyami (Ankara Univ Press, 2018)This study was conducted to evaluate the pineal glands of the foal and adult horses with histomorphometry. The pineal glands were sectioned at a thickness of 40 mu m and stained with AgNOR for stereological analyses. The ... -
Immunohistochemical expression of anti-oxidants in bovine oviduct epithelial cells of estral and luteal phases
Summary: The present study aimed to evaluate immunohistochemical distributions of anti-oxidative enzymes Cu Zn-Superoxide dismutase (SOD-1), catalase, and Glutation peroxidase-1 (GPX1) in the bovine oviduct epithelial cells ... -
In-vivo efficacy of toltrazuril on experimentally induced Toxoplasma gondii tissue cysts in lambs: A novel strategy for prevention of human exposure to meat-borne toxoplasmosis
Kul, Oguz; Yildiz, Kader; Ocal, Naci; Freyre, Alvaro; Deniz, Abdulkerim; Karahan, Siyami; Terzi, Osman Safa (Elsevier Sci Ltd, 2013)The aim of the present study was to investigate in vivo efficacy of toltrazuril on Toxoplasma gondii tissue cysts following induction of chronic toxoplasmosis in 4-week-old lambs (n = 27) by inoculation of 1 x 105 T. gondii ... -
Investigation of Mast Cell Distribution in the Ovine Oviduct During Oestral and Luteal Phases of the Oestrous Cycles
Kurum, Aytul; Ozen, Asuman; Karahan, Siyami; Ozcan, Ziya (Kafkas Univ, Veteriner Fakultesi Dergisi, 2014)Mast cells are heterogeneous cell populations that play significant roles in many organs and systems and involve various physiological processes. We aimed to evaluate mast cells in the ovine oviduct mucosa by means of their ... -
Investigation of mast cell distribution in the ovine oviduct during oestral and luteal phases of the qestrous cycles
Kürüm, Aytül; Özen, Asuman; Karahan, Siyami; Özcan, Ziya (2014)Mast hücreleri birçok organ ve sistemdeki çeşitli fizyolojik süreçlerde önemli rolleri bulunan heterojen hücre topluluğudur. Bu çalışmada koyun ovidukt mukozasındaki mast hücrelerini boyanma özellikleri ve ince yapı düzeyinde ... -
Investigation of the Efficacy of Algan Hemostatic Agent in Liver Laceration Model in Rats
Midi, Ahmet; Kumandaş, Ali; Ekici, Hüsamettin; Bayraktar, Feyzanur; Karapirli, Kübra; Karahan, Siyami; Özyürek, H. Emel (2019)Objectives: Bleeding control is crucial in preventing negative consequences by reducing blood loss in surgical operations. The aim of this study is to evaluate the hemostatic effect of a new herbal hemostatic agent called ... -
İlaç aktif madde yüklü hyaluronik asit nanopartiküllerin sentezi ve eklem dejenerasyonlarında kullanımının değerlendirilmesi
Karahan, Siyami; Kırıkkale Üniversitesi, Rektörlük, Projeler (KırıkkaleKırıkkale Üniversitesi, 2017)…